Comparative analysis of the annotation systems of Mus musculus high density expression microarray
نویسندگان
چکیده
Annotations created by microarrays producer Affymetrix are based on the genomic and transcriptomic knowledge that was available at a time of construction of a particular chip. However scientific databases are regularly updated so there is a need of performing re-annotation processes. The goal of this work was to assess the relevance of the probes located on the given Affymetrix 3’ expression or promoter microarray and to perform a re-annotation procedure. The use of updated definition files proved that they can improve the results of the microarray data analysis comparing to the standard Affymetrix approach.
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